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What is Cannabigerol - CBG?

Updated: Jun 7, 2020

Cannabigerol (CBGA) is considered the mother of cannabinoids. CBG is a minor cannabinoid because it is present at very low levels in the hemp plants derived from Cannabis sativa. Cannabis plants produce cannabigerolic acid (CBGA). When exposed to light and heat, CBGA converts to either CBD, THC, or CBC.

When considering the medicine that best suits you, it’s helpful to know the science behind a strain’s cannabinoid profile. Lab testing has been helpful to scientists to understand the subtle differences between the hemp plants. Phytocannabinoids such as THC and CBD were the main parts of the hemp plant which has been the focus of breeders for years. With the advancements in technology, people are now starting to learn more about how the minor cannabinoids also play a big role in the effectiveness of the plant as a whole.

Cannabigerolic Acid (CBGA) Is The Primary Cannabinoid

Cannabigerolic acid is the precursor to the three major cannabinoids:tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), and cannabichromenic acid (CBCA). There are natural enzymes, called synthases, that breakdown CBGA. It is then converted to three desired cannabinoids mentioned above.

“ Industrial Hemp strains test much higher for CBG. Most strains of medicinal cannabis test less than 10% but some industrial hemp strains have been tested to have as high as 94% CBG with as low as 0.001% THC.”

When exposed to heat, or prolonged UV light, most cannabinoids lose a molecule of carbon dioxide (CO2). This converts them to their neutral form which includes CBG, THC, CBD, CBC, and so forth. In most medicinal tinctures, CBGA is immediately converted to another cannabinoid due to the heating during the extraction process. However, you can find hemp flower strains high in CBGA, then you can ingest it or use smokable forms that cause it to change to cannabigerol (CBG).

Benefits of CBG

There has been very limited research on the benefits of CBG. However, they have found that CBG provides synergy and balance to the other cannabinoids.

With that said, most of the research point shows that CBD is considered to counteract the CB-1 receptor and its effects on the central brain. Why is this important to know? Because CBD oil can be used to counteract some paranoid and heady high feelings that are associated with preparations that have a high amount of THC. CBG oil has the ability to counteract the effects as well. If you are elderly or a first time user of cannabis products you may experience side effects to cannabis oil. To counteract these effects, you can consider taking CBD oils high in CBG to counteract those weird feelings and still get the medicinal benefits of the low THC oil. One way to provide this benefit is to take the CBD oil as an at regular interval and use the low THC oil as a rescue when you do experience feeling such as lack of appetite.

Cannabigerol (CBG) has also been determined to affect the CB2-receptor, which influences the body more. However, researchers aren’t sure if CBG promotes or inhibits CB2-receptor activity yet. Remember that the CB2 receptor is the same receptor that CBD has effects on. The activation of these receptors plays a more role in reducing inflammation. Another effect cannabigerol (CBG) has on the brain is inhibiting the reuptake of GABA, a brain chemical that determines how much stimulation a neuron needs to cause a reaction. When GABA is inhibited then it can decrease anxiety and muscle tension.

CBG is one of many other cannabinoids in the hemp plants that have beneficial effects on our bodies. At Pure Therapy MD, the products are formulated with these beneficial medicinal effects in mind. The products in our Pure Therapy MD that contain CBG include Pure Immune tincture, Joy Hemp Flower, and Calm Hemp flower. The product line also carries a variety of HEMP OIL CREAMS, HEMP FLOWERS, ROLL ON CBD oils, and PAIN RELIEF CREAMS. To learn more about the physician formulated product line, visit www.


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