Is there a natural way to effectively treat your pain without major side effects?
As the usage of cannabinoids gains more acceptance in our society, the medical community will start to accept and embrace the change that comes along with it. Most physicians do not necessarily oppose the usage of cannabinoids but have concerns and curiosity regarding the usage and safety of the products. Recently, there have been a couple of studies that shed light on the widespread usage of cannabinoids compounds for treating pain and the best practice approach to protect patients.
Examining public opinions, attitudes
The American Society of Anesthesiologists (ASA) performed a nationwide study to help better understand the patient's knowledge and attitudes towards CBD. 75% of respondents who expressed interest in using cannabis or cannabinoids for pain management because they felt that these compounds were safer or had fewer adverse effects than opioids and other medications (1). Fifty-eight percent of the respondents believed cannabis and cannabinoid agents have fewer adverse effects than other prescription medications. Perhaps the most surprising was that 40% of the respondents believed that the FDA approved the CBD sold at grocery stores.
In order to understand why CBD works for pain, you have to understand the chemistry of CBD on receptors. The discovery of the Endocannabinoids System (ECS) is arguably the most important discovery in human physiology. Research has revealed that the ECS is responsible for maintaining and controlling the body’s homeostasis, or balanced regulation of every system in the body through two known receptors called CB1 & CB2. While the body produces its own endogenous cannabinoids, many scientists suggest that most people are now suffering from “Cannabinoid Deficiency”. Supplementing our diets with full spectrum phytocannabinoids may be an essential component to achieving optimal health.
There are two primary cannabinoid receptors are identified as Cannabinoid Type 1 receptors (CB1-R) and Cannabinoid Type 2 receptors (CB2-R). The CB1 receptors are located primarily in the brain and the spinal cord. CB2 receptors are located throughout the rest of our body.
1. The receptors can be “unlocked” by three kinds of cannabinoids:
Endocannabinoids Endogenous-fatty-acid cannabinoids produced naturally in the body (e.g., anandamide and 2-AG)
2. Phytocannabinoids concentrated in the oily resin of the buds and leaves of plants such as cannabis (e.g., THC and CBD)
3. Synthetic Cannabinoids Manufactured by artificial means such as in a laboratory (e.g. Marinol and Epidiolex).
When these receptors are unlocked through the presence of Cannabinoids, it causes the ECS to become more active which leads to benefits in pain, sleep, anxiety and much more.
Two Key Natural Endocannabinoids FOUND IN OUR BODY
Anandamide borrows its name from the Sanskrit word ananda, which means joy, bliss, and delight. Nicknamed the “bliss molecule,” anandamide could be a cannabinoid ally against depression and anxiety and has been shown to modulate mood, memory, appetite, fertility, and is even believed to halt the proliferation of cancer cells.
Arachidonoyl glycerol (2-AG ) is the most abundant endocannabinoid in our bodies. It binds very strongly to the CB1 and CB2 receptors embedded throughout the central and peripheral nervous system, and it behaves similarly to tetrahydrocannabinol (THC). 2-AG is believed to regulate sleep, immunity, pain, and appetite.
•THC’s chemical structure is similar to the brain chemical anandamide.
Endocannabinoids such as anandamide function as neurotransmitters because they send chemical messages between nerve cells (neurons) throughout the nervous system. They affect brain areas that influence pleasure, memory, thinking, concentration, movement, coordination, and sensory and time perception.
•THC acts like anandamide by binding directly to the CB1 receptors throughout the nervous system.
Cannabidiol doesn’t bind to the CB1 receptor directly like THC does, CBD blocks the ability of THC to bind to its CB1 receptors. CBD blocks the psychoactive effects of THC which is why people don’t feel as “high” when using CBD-rich products compared to when they consume oils with a higher content of THC.
Scientists know that CBD has an overall anti-inflammatory/immunosuppressive effect by reducing the production of pro-inflammatory cytokines and inhibiting T-Cell function. What this translates is that CBD helps pain through decreasing inflammation.
Please visit www.puretherapymd.com or our store in Alpharetta, Georgia to find out about the products that we have. We offer fast shipping to ensure that you can get our oils in hand to start to experience the benefits of CBD for yourself in no time.